Brothers is a surname. Notable people with the surname include:
Cary Brothers, American singer-songwriter
Fletcher Brothers, American fundamentalist preacher and author
Jim Brothers (1941–2013), American sculptor
Joyce Brothers (1927–2013), American psychologist and columnist
Kerry Brothers, Jr., American songwriter
Leo Vincent Brothers, American gangster and murderer
Paul Brothers, Canadian television personality
Paul Brothers (Canadian football), American football player
Peter Malam Brothers, Battle of Britain Pilot
Rex Brothers, American baseball player
Richard Brothers, Canadian religious leader and author
Vincent Brothers, American mass murderer
