Broadly neutralizing HIV 1 antibodies

Broadly Neutralizing HIV-1 Antibodies (bNAbs) are neutralizing antibodies which neutralize multiple HIV-1 viral strains. In contrast, non-bNAbs are specific for individual viral strains. The discovery of bNAbs has led to an important area of research, namely, discovery of a vaccine, not only limited to HIV, but also other rapidly mutating viruses like Influenza, etc.

The following table shows the characteristics of various HIV-1 bNAbs

Recent years have seen an increase in HIV-1 bNAb discovery.

Online databases like bNAber and LANL constantly report and update the discovery of new HIV bNAbs.