Brindle is a surname. Notable people with the name include:
Arran Brindle (born 1981), English cricketer, member of the England Women's team
Dave Brindle, Canadian broadcast journalist and producer
Frederick Brindle (born 1909), English professional rugby league footballer
Melbourne Brindle (1904–1995), Australian-American illustrator and painter
Reginald Brindle (1925–1998), English cricketer
Reginald Smith Brindle (1917–2003), British composer and writer
Robert Brindle (1837–1916), English prelate of the Roman Catholic Church
Timothy Brindle (born 1980), American Christian hip hop musician
Tom Brindle (disambiguation), multiple people, including:
Tom Brindle (footballer) (1861–1905), English footballer
Tom Brindle (politician) (1878–1950), member of the New Zealand Legislative Council