Brewis is a surname. Notable people with the surname include:
Anne Brewis, daughter of Roundell Cecil Palmer, 3rd Earl of Selborne
Bobby Brewis, the last known human case of foot-and-mouth disease in Britain
Hannes Brewis (1920–2007), South African rugby union player
Henry Brewis (artist) (1932–2000), English artist and poet
John Brewis, British politician and barrister
Peter Brewis, British composer and musician
Robert Brewis, English footballer
Tom Brewis (1907–1975), English footballer
