Brereton is a surname. Notable people with the surname include:
Alexander Picton Brereton (1892-1976), Canadian recipient of the Victoria Cross
Ben Brereton, (born 1999), English footballer
Cuthbert A. Brereton (1850-1910), British civil engineer
Dan Brereton (born 1965), American artist and illustrator
Dermott Brereton (born 1964), Australian rules footballer
Frederick Sadleir Brereton (1852–1957), British author
Henry E. H. Brereton (1865–1957), New York politician
John Brereton (disambiguation), several people
Joseph Lloyd Brereton (1822-1901), English educational reformer and writer
Kevin Brereton (born 1972), Canadian singer, songwriter and record producer
Laurie Brereton (born 1946), Australian politician
Lewis H. Brereton (1890-1967), American military aviation pioneer
Mocky Brereton, New Zealand rugby league footballer
Patrick Brereton, author and academic at Dublin City University
Robert Maitland Brereton (1834–1911), English railway engineer
Robert Pearson Brereton (1818–1894), British engineer and colleague of Isambard Kingdom Brunel
Thomas Brereton (1782-1831), Irish soldier, governor of Senegal
William Brereton (disambiguation), several people