Breen is a surname. Notable people with the surname include:
Abs Breen (born 1979), English DJ and former member of the band Five
Barry Breen, a former Australian rules footballer
Bobby Breen (1927–2016), a Canadian-born American actor and singer
Chris Breen (editor), an editor and writer for Macworld magazine
Chris Breen (ice hockey) (born 1989), Canadian ice hockey player
Craig Breen (born 1990), Irish rally driver
Dan Breen (1894–1969), Irish freedom fighter and a Fianna Fáil politician
Edward D. Breen, American business executive
Edward G. Breen (1908-1991), American politician
Gary Breen (born 1973), Irish footballer
George Breen (born 1935), American freestyle swimmer
Harry Breen, Northern Irish police officer
Jim Breen (born 1947), linguist and Research Fellow at Monash University
John Breen (1896–1964) World War II Royal Air Force commander
Joseph Breen (1890–1965), American film censor, founded the Legion of Decency in 1934
Joe Breen, Canadian football player
Marie Breen (1902–1993), Australian Senator
Mike Breen, American sportscaster
Neil Breen, American film maker
Olivia Breen (born 1996), British athlete
Patrick Breen (born 1960), an American actor, playwright and screenwriter
Shannon Breen (born 1989), American football player
Suzanne Breen, Northern Ireland editor for the Sunday Tribune
T. H. Breen, American historian
Walter H. Breen (1928–1993), numismatist and pederast, husband of SF writer Marion Zimmer Bradley
Vegard Breen (born 1990), Norwegian cyclist