Brazelton is a surname. Notable people with the surname include:
Conni Marie Brazelton (born 1955), American film and television actress appearing on ER (TV series)Dewon Brazelton (born 1980), major league pitcher currently a free agentKitty Brazelton (born 1951), American vocalist, composer, flutist, and lead singer of the band DadadahRalph Brazelton Peck (1912–2008), civil engineer specializing in soil mechanicsT. Berry Brazelton (born 1918), pediatrician and author in the United StatesTyrone Brazelton (born 1986), American professional basketball playerWilliam Brazelton, outlaw and stage robber of the Wild West