Brandenburg is a surname. Notable people with the surname include:
Bryan Brandenburg (born 1959), American writer and video game designer
Chet Brandenburg (1897–1974), American actor
Ed Brandenburg (1893–1968), American actor
Erich Brandenburg (1868–1946), German historian
Hubertus Brandenburg (1923–2009), German-born Swedish Roman Catholic bishop
Jim Brandenburg (born 1945), American environmentalist and photographer
Johannes Brandenburg (1910–1942), German Luftwaffe pilot
Karlheinz Brandenburg (born 1954), German audio engineer and inventor
Mark Brandenburg (politician) (born 1955), American politician
Otto Brandenburg (1934–2007), Danish musician, singer, actor and film score composer
Rick Brandenburg (born 1955), American entomologist
William H. Brandenburg, United States Army Major General
