Box is a surname. Notable people with the surname include:
Ab Box (1909–2000), Canadian football playerBetty Box (1915–1999), British film producerCloyce Box (1923–1993), American football playerDon Box, Microsoft employeeEdgar Box, pseudonym used by Gore VidalGeorge E. P. Box (1919–2013), British statisticianGodfrey Box, 16th century British entrepreneurJason Box, American glaciologistJohn Box (1920–2005), British film designerKenneth Box (born 1930), British track and field sprinterMick Box (born 1947), British guitaristMuriel Box (1905–1991), British writerSteve Box (born 1967), British animatorSydney Box (1907–1983), British film producer