Box is a surname. Notable people with the surname include:
Ab Box (1909–2000), Canadian football player
Betty Box (1915–1999), British film producer
Cloyce Box (1923–1993), American football player
Don Box, Microsoft employee
Edgar Box, pseudonym used by Gore Vidal
George E. P. Box (1919–2013), British statistician
Godfrey Box, 16th century British entrepreneur
Jason Box, American glaciologist
John Box (1920–2005), British film designer
Kenneth Box (born 1930), British track and field sprinter
Mick Box (born 1947), British guitarist
Muriel Box (1905–1991), British writer
Steve Box (born 1967), British animator
Sydney Box (1907–1983), British film producer
