Bottomley is an English surname. Notable people with the surname include:
Arthur Bottomley (1907 –1995), British Labour politicianGordon Bottomley (1874 – 1948), English poetHoratio Bottomley, British fraudsterJames Bottomley (diplomat) (1920–2013), British diplomatJim Bottomley, baseball playerJohn Bottomley, a Canadian singer-songwriterNorman Bottomley, senior Royal Air Force commanderPeter Bottomley, a British Conservative politicianVirginia Bottomley (born 1948), British politicianWilliam Lawrence Bottomley, American architect