Trisha Shetty (Editor)

Bornyl diphosphate synthase

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EC number
  
5.5.1.8

IntEnz
  
IntEnz view

ExPASy
  
NiceZyme view

CAS number
  
72668-91-8

BRENDA
  
BRENDA entry

KEGG
  
KEGG entry

In enzymology, a bornyl diphosphate synthase (EC 5.5.1.8) is an enzyme that catalyzes the chemical reaction

geranyl diphosphate (+)-bornyl diphosphate

Hence, this enzyme has one substrate, geranyl diphosphate, and one product, (+)-bornyl diphosphate.

This enzyme belongs to the family of isomerases, specifically the class of intramolecular lyases. The systematic name of this enzyme class is (+)-bornyl-diphosphate lyase (decyclizing). Other names in common use include bornyl pyrophosphate synthase, bornyl pyrophosphate synthetase, (+)-bornylpyrophosphate cyclase, and geranyl-diphosphate cyclase (ambiguous). This enzyme participates in monoterpenoid biosynthesis.

Structural studies

As of late 2007, 7 structures have been solved for this class of enzymes, with PDB accession codes 1N1B, 1N1Z, 1N20, 1N21, 1N22, 1N23, and 1N24.

References

Bornyl diphosphate synthase Wikipedia