Entrez 651 | Ensembl ENSG00000152785 | |
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External IDs OMIM: 112263 MGI: 88179 HomoloGene: 927 GeneCards: BMP3 | ||
Bone morphogenetic protein 3, also known as osteogenin, is a protein in humans that is encoded by the BMP3 gene.
The protein encoded by this gene is a member of the transforming growth factor beta superfamily. It, like other bone morphogenetic proteins (BMP's) is known for its ability to induce bone and cartilage development. It is a disulfide-linked homodimer. It negatively regulates bone density. BMP3 is an antagonist to other BMP's in the differentiation of osteogenic progenitors.
It is highly expressed in fractured tissues.
References
Bone morphogenetic protein 3 Wikipedia(Text) CC BY-SA