Bone is a surname. Notable people with the surname Bone include:
Adrián Bone (born 1988), Ecuadorian footballer
Alex Bone (born 1971), Scottish footballer
Deborah Bone (1963–2014), British mental health nurse
Drummond Bone, British academic, expert on Byron
Edith Bone (1889–1975), Hungarian medical professional, journalist and translator
Edwina Bone (born 1988), Australian field hockey player
Eleanor Bone (1911–2001), English Wiccan
Gavin Bone (born 1964), English author and lecturer in the fields of magic and witchcraft
Henry Pierce Bone (1779–1855), English enamel painter
Homer Bone (1883–1970), United States federal judge and Senator from Washington
Ian Bone (born 1947), English anarchist
Ian Bone (author) (born 1956), Australian writer, author and novelist
James Bone (1872–1962), British journalist and London editor of The Guardian
Jimmy Bone (born 1949), Scottish footballer
John Bone (disambiguation), multiple people, including:
John Bone (bishop) (1930–2014), British religious leader
John T. Bone (born 1947), British-born actor
John Gavin Bone (born 1914), Scottish Olympic cyclist
Kelsey Bone (born 1991), American basketball player
Ken Bone (born 1958), American basketball coach
Mick Bone (born 1942), Australian rules footballer
Muirhead Bone (1876–1953), Scottish artist
Peter Bone (born 1952), British politician
Philip J. Bone (1873–1964), English mandolinist and guitar play
Phyllis Bone (1894–1972), Scottish sculptor
Ponty Bone, American accordionist
Randall Bone (born 1973), Australian rules footballer
Robert Trewick Bone (1790–1840), English painter of sacred, classical and genre scenes
Scott Cordelle Bone (1869–1936), American politician, founded Iditarod Trail Sled Dog Race, Governor of Alaska
Stephen Bone (1904–1958), English artist and writer
Tiberiu Bone (1929–1983), Romanian footballer