Bloodworth is an English surname derived possibly from Blidworth in Nottinghamshire or from a similar toponym. Notable people with the surname include:
James Bloodworth Jr. (1925–2006), American physician and pathologist
Jimmy Bloodworth (1917–2002), American baseball player
Margaret Bloodworth, former Canadian National Security Advisor
Rhoda Alice Bloodworth (1889–1980), New Zealand labour activist, community worker and feminist
Sandra Bloodworth, Australian labour historian and socialist activist
Sir Thomas Bloodworth (1620–1682), English merchant and politician; Lord Mayor of London during the Great Fire of London (1666)
Thomas Bloodworth (New Zealand politician) (1882–1974), New Zealand politician
Timothy Bloodworth (1736–1814), American teacher and statesman from North Carolina
Linda Bloodworth-Thomason (born 1947), American writer and television producer
