Symbol IRES_Bip Rfam RF00223 Domain(s) Eukaryota | Alt. Symbols Bip_IRES RNA type Cis-reg; IRES GO 0043022 | |
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The BiP internal ribosome entry site (IRES) is an RNA element present in the 5' UTR of the mRNA of BiP protein and allows cap-independent translation. BiP protein expression has been found to be significantly enhanced by the heat shock response due to internal ribosome entry site (IRES)-dependent translation. It is thought that this translational mechanism is essential for the survival of cells under stress [1].
References
Bip internal ribosome entry site (IRES) Wikipedia(Text) CC BY-SA