EC number 6.3.4.10 IntEnz IntEnz view ExPASy NiceZyme view | CAS number 37318-67-5 BRENDA BRENDA entry KEGG KEGG entry | |
In enzymology, a biotin-[propionyl-CoA-carboxylase (ATP-hydrolysing)] ligase (EC 6.3.4.10) is an enzyme that catalyzes the chemical reaction
ATP + biotin + apo-propionyl-CoA:carbon-dioxide ligase (ADP-forming)The 3 substrates of this enzyme are ATP, biotin, and [[apo-[propionyl-CoA:carbon-dioxide ligase (ADP-forming)]], whereas its 3 products are AMP, diphosphate, and propionyl-CoA:carbon-dioxide ligase (ADP-forming).
This enzyme belongs to the family of ligases, specifically those forming generic carbon-nitrogen bonds. The systematic name of this enzyme class is biotin:apo-[propanoyl-CoA:carbon-dioxide ligase (ADP-forming)] ligase (AMP-forming). Other names in common use include biotin-[propionyl-CoA-carboxylase (ATP-hydrolysing)] synthetase, biotin-propionyl coenzyme A carboxylase synthetase, and propionyl coenzyme A holocarboxylase synthetase. This enzyme participates in biotin metabolism.