Type ? Target ACVR2B CAS Number 1356922-05-8 | Source Human ATC code none ChemSpider none | |
Bimagrumab (BYM338) is a human monoclonal antibody developed by Novartis to treat pathological muscle loss and weakness. On August 20, 2013 it was announced that bimagrumab was granted breakthrough therapy designation for sporadic inclusion body myositis (sIBM) by US Food and Drug Administration.
Bimagrumab is currently entering Phase II development, with some research indicating clinical effects. In 2016, Novartis intends to apply for FDA approval to treat sIBM patients with Bimagrumab BYM338.
April 2016 Novartis said that its “breakthrough” drug bimagrumab (BYM338) failed a Phase IIb/III study for sporadic inclusion body myositis.
References
Bimagrumab Wikipedia(Text) CC BY-SA