Species Human Entrez 6822 | Human Mouse Ensembl ENSG00000105398 | |
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Aliases SULT2A1, DHEA-ST, DHEAS, HST, ST2, ST2A1, ST2A3, STD, hSTa, sulfotransferase family 2A member 1 External IDs MGI: 98430 HomoloGene: 37741 GeneCards: SULT2A1 | ||
Bile salt sulfotransferase also known as hydroxysteroid sulfotransferase (HST) or sulfotransferase 2A1 (ST2A1) is an enzyme that in humans is encoded by the SULT2A1 gene.
Function
Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. This gene is primarily expressed in liver and adrenal tissues where the encoded protein sulfonates steroids and bile acids.
References
Bile salt sulfotransferase Wikipedia(Text) CC BY-SA