Bianchini is an Italian surname. Notable people with the surname include:
Angela Bianchini (born 1921), Italian fiction writer and literary critic
Brian Bianchini (1978–2004), American male model
Francesco Bianchini (1662–1729), Italian philosopher and scientist
Joseph Bianchini (1704-?), Francesco's nephew, Italian topographer and writer
Federico Bianchi (painter), Italian Baroque painter
Federico Bianchi (soccer) (born 1983), American former professional soccer player
Gina Bianchini, founder of the Ning social networking platform
Giovanni Bianchini (1410–c. 1449), Italian astronomer
Giuseppe Bianchini (1704—1764), Italian Oratorian, biblical, historical, and liturgical scholar
Leslie Bianchini (born 1947), Playboy magazine Playmate of the Month
Orlando Bianchini (born 1955), Italian hammer thrower
Vincenzo Bianchini (1903—2000) Italian artist
