Samiksha Jaiswal (Editor)

Beta phosphoglucomutase

Updated on
Edit
Like
Comment
Share on FacebookTweet on TwitterShare on LinkedInShare on Reddit
EC number
  
5.4.2.6

IntEnz
  
IntEnz view

ExPASy
  
NiceZyme view

CAS number
  
68651-99-0

BRENDA
  
BRENDA entry

KEGG
  
KEGG entry

In enzymology, a beta-phosphoglucomutase (EC 5.4.2.6) is an enzyme that catalyzes the chemical reaction

beta-D-glucose 1-phosphate beta-D-glucose 6-phosphate

Hence, this enzyme has one substrate, beta-D-glucose 1-phosphate, and one product, beta-D-glucose 6-phosphate.

This enzyme belongs to the family of isomerases, specifically the phosphotransferases (phosphomutases), which transfer phosphate groups within a molecule. The systematic name of this enzyme class is beta-D-glucose 1,6-phosphomutase. This enzyme participates in starch and sucrose metabolism.

Structural studies

20 structures have been solved for this enzyme PDB. Some of the accession codes are 1LVH, 1O03, 1O08, 1Z4N, 1Z4O, and 1ZOL. Most of these structures detail metal fluoride analogue complexes which are used to mimic different states along the reaction coordinate.

References

Beta-phosphoglucomutase Wikipedia