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Beta lysine 5,6 aminomutase

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EC number
  
5.4.3.3

IntEnz
  
IntEnz view

ExPASy
  
NiceZyme view

CAS number
  
9075-69-8

BRENDA
  
BRENDA entry

KEGG
  
KEGG entry

In enzymology, a beta-lysine 5,6-aminomutase (EC 5.4.3.3) is an enzyme that catalyzes the chemical reaction

(3S)-3,6-diaminohexanoate (3S,5S)-3,5-diaminohexanoate

Hence, this enzyme has one substrate, (3S)-3,6-diaminohexanoate, and one product, (3S,5S)-3,5-diaminohexanoate.

This enzyme belongs to the family of isomerases, specifically those intramolecular transferases transferring amino groups. The systematic name of this enzyme class is (3S)-3,6-diaminohexanoate 5,6-aminomutase. Other names in common use include beta-lysine mutase, and L-beta-lysine 5,6-aminomutase. This enzyme participates in lysine degradation. It employs one cofactor, cobamide.

Structural studies

As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code 1XRS.

References

Beta-lysine 5,6-aminomutase Wikipedia