Besson is a French surname. Notable people with the surname include:
Albert Besson, French physician
Antoine-Marie-Benoît Besson, French army general during world war two
Benno Besson, Swiss actor and film director
Colette Besson, French athlete
Éric Besson, French minister
Frank S. Besson, Jr., U.S. Army general
Gustave Auguste Besson (1820-1874), brass instrument maker
Hyacinthe Besson (1816–1861), a French painter and missionary priest
Jacques Besson (1540? - 1573), French inventor
Louis Besson, French minister
Luc Besson, film director
Philippe Besson, French writer