Besser is the surname of:
Chaskel Besser (born 1923), Rabbi from ManhattanJoe Besser (1907–1988), American comedianLes Besser, founder of Compact Software, the first RF and microwave EDA companyMatt Besser (born 1967), best known from the sketch comedy show Upright Citizens BrigadeRobert Dennis Besser, see Robert DenningWilibald Swibert Joseph Gottlieb von Besser (1784–1842), Austrian botanistJesse Besser, who invented a machine for making Besser blocks.