Benzoyl CoA 2,3 dioxygenase

Benzoyl-CoA 2,3-dioxygenase (EC 1.14.12.21, benzoyl-CoA dioxygenase/reductase, BoxBA, BoxA/BoxB system) is an enzyme with systematic name benzoyl-CoA,NADPH:oxygen oxidoreductase (2,3-hydroxylating). This enzyme catalyses the following chemical reaction

benzoyl-CoA + NADPH + H⁺ + O₂ ⇌ 2,3-dihydro-2,3-dihydroxybenzoyl-CoA + NADP⁺

Benzoyl-CoA 2,3-dioxygenase is involved in aerobic benzoate metabolism in Azoarcus evansii.