Density 1.18 g/cm³ Appearance Colorless liquid | Boiling point 35 °C | |
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1,2-Benzisoxazole is an aromatic organic compound with a molecular formula C7H5NO containing a benzene-fused isoxazole ring structure. The compound itself has no common applications; however, functionalized benzisoxazoles and benzisoxazoyls have a variety of uses, including pharmaceutical drugs such as some antipsychotics (including risperidone, paliperidone, ocaperidone, and iloperidone) and the anticonvulsant zonisamide.
Its aromaticity makes it relatively stable; however, it is only weakly basic.
Synthesis
Benzisoxazole may be prepared from inexpensive salicylaldehyde, via a base catalyzed room temperature reaction with hydroxylamine-O-sulfonic acid.
References
Benzisoxazole Wikipedia(Text) CC BY-SA