Baglioni is an Italian surname. Notable people with the surname include:
Claudio Baglioni (1951-) Italian musician
Piero Baglioni (1952-), Italian chemist and University professor at the University of Florence
Giovanni Baglione (1566–1643), Italian early Baroque painter and historian of art
Cesare Baglioni (c. 1525-1590), Italian painter of the Renaissance period
Baglioni (family) or one of its members:
Rodolfo Baglioni (1512-1554), Italian condottiero serving in the Imperial army
Astorre Baglioni
Malatesta Baglioni the Elder (died 1437), ruler of Cannara, Spello and Bastia Umbra
Malatesta Baglioni the Younger (1491-1531), ruler of Perugia
Grifonetto Baglioni
Gian Paolo Baglioni condottiero and nemesis of Cesare Borgia
Baglioni Hotel an Italian hotel firm with branches in London, Milan and other locations.