Symbol BNR Pfam clan CL0434 SCOP 1euu | Pfam PF02012 InterPro IPR002860 SUPERFAMILY 1euu | |
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Bacterial neuraminidase is type of neuraminidase and a virulence factor for many bacteria including Bacteroides fragilis and Pseudomonas aeruginosa. Its function is to cleave a sialic acid residue off ganglioside-GM1 (a modulator of cell surface and receptor activity) turning it into asialo-GM1 to which type 4 pilli (attachment factors) bind preferentially.
References
Bacterial neuraminidase Wikipedia(Text) CC BY-SA