Entrez 10902 | Ensembl ENSG00000112983 | |
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Aliases BRD8, SMAP, SMAP2, p120, bromodomain containing 8 External IDs MGI: 1925906 HomoloGene: 41790 GeneCards: BRD8 |
Bromodomain-containing protein 8 is a protein that in humans is encoded by the BRD8 gene.
The protein encoded by this gene interacts with thyroid hormone receptor in a ligand-dependent manner and enhances thyroid hormone-dependent activation from thyroid response elements. This protein contains a bromodomain and is thought to be a nuclear receptor coactivator. Three alternatively spliced transcript variants that encode distinct isoforms have been identified.
Interactions
BRD8 has been shown to interact with Thyroid hormone receptor beta and Retinoid X receptor alpha.
References
BRD8 Wikipedia(Text) CC BY-SA