Neha Patil (Editor)

BRD8

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Species
  
Entrez
  
10902

Human
  
Ensembl
  
ENSG00000112983

BRD8

Aliases
  
BRD8, SMAP, SMAP2, p120, bromodomain containing 8

External IDs
  
MGI: 1925906 HomoloGene: 41790 GeneCards: BRD8

Bromodomain-containing protein 8 is a protein that in humans is encoded by the BRD8 gene.

The protein encoded by this gene interacts with thyroid hormone receptor in a ligand-dependent manner and enhances thyroid hormone-dependent activation from thyroid response elements. This protein contains a bromodomain and is thought to be a nuclear receptor coactivator. Three alternatively spliced transcript variants that encode distinct isoforms have been identified.

Interactions

BRD8 has been shown to interact with Thyroid hormone receptor beta and Retinoid X receptor alpha.

References

BRD8 Wikipedia


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