Species Human Entrez 60468 | Human Mouse Ensembl ENSG00000112182 | |
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Aliases BACH2, BTBD25, BTB domain and CNC homolog 2 External IDs MGI: 894679 HomoloGene: 7240 GeneCards: BACH2 | ||
Transcription regulator protein BACH2 is a protein that in humans is encoded by the BACH2 gene. It contains a BTB/POZ domain at its N-terminus which forms a disulphide-linked dimer and a bZip_Maf domain at the C-terminus.
Model organisms
Model organisms have been used in the study of BACH2 function. A conditional knockout mouse line called Bach2tm1a(EUCOMM)Wtsi was generated at the Wellcome Trust Sanger Institute. Male and female animals underwent a standardized phenotypic screen to determine the effects of deletion. Additional screens performed: - In-depth immunological phenotyping - in-depth bone and cartilage phenotyping
References
BACH2 Wikipedia(Text) CC BY-SA