Ayers is a surname. Notable people with the surname include:
A.D. Ayers, National League umpire
Bill Ayers, a professor at the University of Illinois at Chicago and a former member of the revolutionary organization Weather Underground
Edward L. Ayers, president of the University of Richmond
Eli Ayers, first colonial agent of the American Colonization Society
Henry Ayers, former Premier of South Australia
Kevin Ayers, British rock singer
Michael R. Ayers, British philosopher
Nathaniel Ayers, schizophrenic musician whose life was used as a basis for the movie The Soloist starring Jamie Foxx and Robert Downey, Jr.
Randy Ayers, U.S. basketball coach
Ron Ayers, British aeronautical engineer and designer of ThrustSSC
Roy Ayers, funk, soul and jazz vibraphone player
Rufus A. Ayers, Virginia lawyer, businessman, and politician, who served as Attorney General of Virginia
Thomas G. Ayers, Chicago businessman, philanthropist, and father of Bill Ayers
Tony Ayers, former senior Australian public servant
