Ascher is an alternative spelling of Asher and is the surname of:
William Ascher, (born 1947), American professor of public policy
Zika Ascher, (born 1910), Czech refugee textile designer and manufacturer in London and Paris
Joseph Ascher, Dutch composer and court pianist to Eugénie de Montijo
Kate Ascher, an author and executive vice president of the New York City Economic Development Corporation
Kenneth Lee Ascher (born 1944), American jazz pianist & composer
Leo Ascher (1880-1942), Jewish composer
Mathias Ascher (pseudonym of Nathan Birnbaum), Austrian journalist and Jewish philosopher
Saul Ascher (1767-1822), Jewish narrative writer and publicist