EC number 4.1.1.76 IntEnz IntEnz view ExPASy NiceZyme view | CAS number 144713-36-0 BRENDA BRENDA entry KEGG KEGG entry | |
In enzymology, an arylmalonate decarboxylase (EC 4.1.1.76) is an enzyme that catalyzes the chemical reaction
2-aryl-2-methylmalonateHence, this enzyme has one substrate, 2-aryl-2-methylmalonate, and two products, 2-arylpropanoate and CO2.
This enzyme belongs to the family of lyases, specifically the carboxy-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is 2-aryl-2-methylmalonate carboxy-lyase (2-arylpropanoate-forming). Other names in common use include AMDASE, 2-aryl-2-methylmalonate carboxy-lyase, and 2-aryl-2-methylmalonate carboxy-lyase (2-arylpropionate-forming).
Structural studies
As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code 2DGD.
References
Arylmalonate decarboxylase Wikipedia(Text) CC BY-SA