Archaeal transcription factor B (ATFB or TFB) (homologous to eukaryotic TFIIB) is a polypeptide important in archaeal transcription.
Structure
TFB is comprised an amino-terminal region (TFBN) and a larger carboxyl-terminal region (TFBC).
TFBN is approximately one third of the protein and contains both a B-finger motif (homologous to the TFIIB B-finger) and a zinc-finger motif.
TFBC is folded into a globulus which binds to the TATA binding protein (TBP) and to TFB-recognition elements (BRE) upstream of the TATA box. These bindings are important for transcription polarity.
References
Archaeal transcription factor B Wikipedia(Text) CC BY-SA