Girish Mahajan (Editor)

Arbaclofen placarbil

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Pregnancy category
  
N/A

Legal status
  
Development terminated

PubChem CID
  
11281011

Molar mass
  
399.86 g/mol

ATC code
  
none

CAS Number
  
847353-30-4

ChemSpider
  
9456008

Arbaclofen placarbil httpsuploadwikimediaorgwikipediacommonsthu

Arbaclofen placarbil (ar-BAC-loe-fen pla-KAR-bil, also known as XP19986) is a prodrug of R-baclofen. Arbaclofen placarbil possesses more favorable pharmacokinetic profile than baclofen, with less fluctuations in plasma drug levels. It was being developed as a potential treatment for patients with GERD and spasticity due to multiple sclerosis; however, in May 2013 XenoPort announced the termination of development because of unsuccessful results in phase III clinical trials.

References

Arbaclofen placarbil Wikipedia