Apneustic center

The apneustic center (or apneustic area) of the lower pons appears to promote inspiration by stimulation of the I neurons in the medulla oblongata providing a constant stimulus.

The apneustic center of pons sends signals to the dorsal respiratory center in the medulla to delay the 'switch off' signal of the inspiratory ramp provided by the pneumotaxic center of pons. It controls the intensity of breathing. The apneustic center is inhibited by pulmonary stretch receptors. However, it gives positive impulses to the inspiratory (I) neurons.