Antunes is a surname in the Portuguese language, of patronymic origin meaning "son of Anthony (António)".
Notable people with the surname include:
Anderson Andrade Antunes (born 1981), Brazilian footballer
António Lobo Antunes (born 1942), Portuguese writer and psychisatrist
Arnaldo Antunes (born 1960), Brazilian writer and composer
Arthur Antunes Coimbra (born 1953), Brazilian footballer and coach
Cármen Lúcia Antunes Rocha (born 1954), Chief Justice of the Supreme Federal Court of Brazil
Ernesto Melo Antunes (1933–1999), Portuguese politician and general
Hélder F. Antunes (born 1963), Portuguese-American Silicon Valley executive and former racecar driver
João Antunes (1642–1712), Portuguese Baroque architect
João do Canto e Castro Antunes (1862–1934), President of the Portuguese Republic 1918–1919
Joaquim José Antunes (1731–1811), Portuguese harpsichord maker
Jorge Antunes (composer) (born 1942), Brazilian composer
Macaris Antunes do Livramento (born 1960), Brazilian boxer
Manuel Lobo Antunes (born 1958), current Portuguese Ambassador to the United Kingdom
Manuel Antunes Frasquilho (died 2015), Portuguese executive and politician
Miguel Antunes Frasquilho (born 1967), Portuguese President of AICEP Portugal Global and politician
Miguel Telles Antunes (born 1937), Portuguese paleontologist and academic
Sandy Antunes (born 1967), American astronomer and writer
Talita Antunes (born 1982), Brazilian beach volleyball player
Vitorino Antunes (born 1987), Portuguese footballer