Symbol Antifungal_prot InterPro IPR022706 PDB RCSB PDB; PDBe; PDBj | Pfam PF11402 Pfam structures PDBsum structure summary | |
 | ||
In molecular biology, proteins in the antifungal protein family consist of five antiparallel beta strands which are highly twisted creating a beta barrel stabilised by four internal disulphide bridges. A cationic site adjacent to a hydrophobic stretch on the protein surface may constitute a phospholipid binding site.
Human epithelia produce antifungal proteins. The proteins kill fungi by inducing apoptosis and/or forming pores on the cell membrane.
References
Antifungal protein Wikipedia(Text) CC BY-SA