Anti actin antibodies

Anti-actin antibodies (AAA) are found at increased frequency in certain autoimmune diseases and may be of some diagnostic value.

In coeliac disease anti-actin antibodies correlated with the level of intestinal damage.

In autoimmune hepatitis anti-actin antibodies correlate with patterns of immune recognition, the pattern of recognition was specific to a small percentage of auto-immune hepatitis type 1 or cryptogenic hepatitis patients.

In gastric cancer anti-actin antibodies were elevated, along with other antibodies in severe disease with poor outcomes.