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Anti-actin antibodies (AAA) are found at increased frequency in certain autoimmune diseases and may be of some diagnostic value.
In coeliac disease anti-actin antibodies correlated with the level of intestinal damage.
In autoimmune hepatitis anti-actin antibodies correlate with patterns of immune recognition, the pattern of recognition was specific to a small percentage of auto-immune hepatitis type 1 or cryptogenic hepatitis patients.
In gastric cancer anti-actin antibodies were elevated, along with other antibodies in severe disease with poor outcomes.
References
Anti-actin antibodies Wikipedia(Text) CC BY-SA