Symbol AMHR2 HUGO 465 RefSeq NM_020547 | Entrez 269 OMIM 600956 UniProt Q16671 | |
Anti-Müllerian hormone receptor is a receptor for anti-Müllerian hormone.
Pathology
The anti-Müllerian hormone receptor (Müllerian Inhibiting Substance Type II Receptor) can be responsible for persistent Müllerian duct syndrome.
Müllerian inhibiting substance type II receptor (MISIIR), also known as the Anti-Müllerian Hormone Receptor, is expressed by ovarian, breast, and prostate cancers and these cancer cells have been reported to apoptose in response to exposure to the Müllerian inhibiting substance (MIS).
Antibodies have been developed that specifically target MISIIR and may be useful as vehicles for drugs and toxins for targeted cancer therapy.
References
Anti-Müllerian hormone receptor Wikipedia(Text) CC BY-SA