Angerstein is a surname. Notable people with the surname include:
John Angerstein (MP) (c. 1774–1858), English politician and Member of Parliament, son of John Julius
John Julius Angerstein (1732–1823), London merchant and patron of the fine arts
Karl Angerstein (1890–1985), senior Luftwaffe officer of World War II
Reinhold Angerstein (1718–1760), Swedish metallurgist
William Angerstein (1811–1897), British Liberal Party Member of Parliament