Doctoral advisor Tom Blundell | Name Andrej Sali | |
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Institutions University of California, San Francisco
Harvard University
Rockefeller University
Birkbeck College, University of London
University of Ljubljana Alma mater Birkbeck College, University of London Thesis Modelling three-dimensional structure of a protein from its amino acid sequence (1991) Notable students Ilya Vakser
Roberto Sanchez
Andras Fiser
Bino John
Maya Topf
Francisco Melo
M.S. Madhusudhan
Frank Alber
Rachel Karchin
David Barkan | ||
Integrative modeling of biomolecular assembly structures and pathways | Prof. Andrej Sali
Andrej Šali (born 1963, Kranj, Slovenia) is a computational structural biologist. Since 2003, he has been Professor in the Department of Bioengineering and Therapeutic Sciences at University of California, San Francisco. He also serves as an editor of the journal Structure.
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Education
Šali received his Bachelor of Science degree in Chemistry from University of Ljubljana, 1987; his Ph.D. in Molecular Biophysics from Birkbeck College, University of London, 1991 (working with Tom Blundell); and did postdoctoral work at Harvard University (working with Martin Karplus).
Research
Sali joined the faculty of the Rockefeller University in 1995, following his postdoctoral research at Harvard University. He is using computation grounded in the laws of physics and evolution to study the structure and function of proteins. For example, he developed comparative protein structure modeling by satisfaction of spatial restraints, implemented in program MODELLER and integrative structure determination of macromolecular assemblies, implemented in program IMP.
Research impact
Sali contributes to structural biology by developing and applying computational methods for structural modeling and analysis of proteins. The two most often used programs developed by his research group include MODELLER for comparative protein structure modeling and IMP for integrative structure determination.
As of late 2013, Šali published approximately 320 papers, which were cited approximately 36,000 times per Google Scholar. His Hirsch-index is 85 (i.e., 85 publication have been cited at least 85 times).