Ana Maria de Lorena, Duchess of Abrantes (Ana Maria Catarina Henriqueta de Lorena; 3 September 1691 – 1761) was a Portuguese noblewoman. The eldest daughter of Rodrigo Anes de Sa Almeida e Menezes, 1st Marquis of Abrantes and 7th Count of Penaguiao, she adopted the surname "de Lorena" after a maternal great-grandfather, Francois-Louis de Lorraine.
By Royal Decree of King Joseph I of Portugal of 9 December 1753, she was created Duchess of Abrantes vitalicio upon her appointment as The Queen's Maid of Honour (in Portuguese Camareira-Mor), the highest court position for a lady. She inherited her family estates and honours three years later, upon her brother's death. Her younger brother, Joaquim Francisco de Sa Almeida e Menezes, had succeeded their father as 2nd Marquis of Abrantes and married Dona Ana Maria's only daughter, but died without issue; thus, in 1756, she became 3rd Marchioness of Abrantes and 9th Countess of Penaguiao.
Her surname of Lorena (the Portuguese translation for Lorraine) was inherited from her maternal grandmother, Marie-Angelique-Henriette de Lorraine, daughter of Francois-Louis, comte d'Harcourt.
Duquesa Ana Maria married Dom Rodrigo de Mello (1688–1713), second child of Nuno Alvares Pereira de Mello, 1st Duke of Cadaval. They had an only daughter, Maria Margarida de Lorena (likewise created Duchess of Abrantes), who married her uncle (Ana Maria's brother), Dom Joaquim Francisco de Sa Almeida e Menezes, 2nd Marquis of Abrantes.