Amodeo is a surname. Notable people with the name include:
Federico Amodeo (1859–1946), Italian mathematicianJohn Amodeo, American television producerJohn F. Amodeo, (born 1950), American politician from New JerseyMike Amodeo (born 1952), Canadian ice hockey playerOrie Amodeo (1921–1998), American musician, member of the Lawrence Welk orchestraSantiago Amodeo (born 1969), Andalusian film director, screenwriter, musician and composerThomas P. Amodeo (born 1951), American lawyer and judge