Amodeo is a surname. Notable people with the name include:
Federico Amodeo (1859–1946), Italian mathematician
John Amodeo, American television producer
John F. Amodeo, (born 1950), American politician from New Jersey
Mike Amodeo (born 1952), Canadian ice hockey player
Orie Amodeo (1921–1998), American musician, member of the Lawrence Welk orchestra
Santiago Amodeo (born 1969), Andalusian film director, screenwriter, musician and composer
Thomas P. Amodeo (born 1951), American lawyer and judge
