Formula C39H54N10O13S | Molar mass 902.97 g/mol | |
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Appearance Colorless, crystalline solid | ||
Amaninamide is a cyclic nonribosomal peptide. It is one of the amatoxins, all of which are found in several members of the Amanita genus of mushrooms.
Toxicology
Like other amatoxins, amaninamide is an inhibitor of RNA polymerase II. Upon ingestion, it binds to the RNA polymerase II enzyme which completely prevents mRNA synthesis, effectively causing cytolysis of hepatocytes (liver cells) and kidney cells.
References
Amaninamide Wikipedia(Text) CC BY-SA