Rahul Sharma (Editor)

Altinicline

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ATC code
  
None

PubChem CID
  
3036156

UNII
  
RJ9V9V09VM

CAS Number
  
179120-92-4

ChemSpider
  
2300234

ChEMBL
  
CHEMBL111659

Altinicline

Altinicline (SIB-1508Y, SIB-1765F) is a drug which acts as an agonist at neural nicotinic acetylcholine receptors with high selectivity for the α4β2 subtype. It stimulates release of dopamine and acetylcholine in the brain in both rodent and primate models, and progressed as far as Phase II clinical trials for Parkinson's disease, where "no antiparkinsonian or cognitive-enhancing effects were demonstrated", although its current status is unclear.

References

Altinicline Wikipedia