Alsina is a surname. Notable people with the surname include:
Adolfo Alsina (1829–1877), Argentine lawyer and Unitarian politicianAugust Alsina (born 1992), American singerJuan Perez Alsina, Argentine politician for the Salta Renewal PartyLandelino Lavilla Alsina (born 1934), Spanish politicianDr. Manuel F. Alsina Capo (born 1909), prominent Spanish-American urologist surgeonRamón Martí Alsina (1826–1894), Spanish Eclectic painterValentín Alsina (1802–1869), Argentine lawyer and politician