Alpha santonin 1,2 reductase

In enzymology, an alpha-santonin 1,2-reductase (EC 1.3.1.47) is an enzyme that catalyzes the chemical reaction

1,2-dihydrosantonin + NAD(P)+ ⇌ alpha-santonin + NAD(P)H + H⁺

The 3 substrates of this enzyme are 1,2-dihydrosantonin, NAD⁺, and NADP⁺, whereas its 4 products are alpha-santonin, NADH, NADPH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 1,2-dihydrosantonin:NAD(P)+ 1,2-oxidoreductase.