Alpha bisabolene synthase

Alpha-bisabolene synthase (EC 4.2.3.38, bisabolene synthase) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphate-lyase ((E)-alpha-bisabolene-forming). This enzyme catalyses the following chemical reaction

This synthase requires a divalent cation cofactor (Mg²⁺ or, to a lesser extent, Mn²⁺) to neutralize the negative charge of the diphosphate leaving group.