Suvarna Garge (Editor)

Allene oxide cyclase

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EC number
  
5.3.99.6

IntEnz
  
IntEnz view

ExPASy
  
NiceZyme view

CAS number
  
118390-59-3

BRENDA
  
BRENDA entry

KEGG
  
KEGG entry

In enzymology, an allene-oxide cyclase (EC 5.3.99.6) is an enzyme that catalyzes the chemical reaction

(9Z)-(13S)-12,13-epoxyoctadeca-9,11,15-trienoate (15Z)-12-oxophyto-10,15-dienoate

Hence, this enzyme has one substrate, (9Z)-(13S)-12,13-epoxyoctadeca-9,11,15-trienoate, and one product, (15Z)-12-oxophyto-10,15-dienoate.

This enzyme belongs to the family of isomerases, specifically a class of other intramolecular oxidoreductases. The systematic name of this enzyme class is (9Z)-(13S)-12,13-epoxyoctadeca-9,11,15-trienoate isomerase (cyclizing).

Structural studies

As of late 2007, 6 structures have been solved for this class of enzymes, with PDB accession codes 1Z8K, 1ZVC, 2BRJ, 2DIO, 2GIN, and 2Q4I.

References

Allene-oxide cyclase Wikipedia